Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 13/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8266062 | 0.83 | MAPK14 (0.62) | MAPK14PTGS2PTGS1ACHE | |
| SCHEMBL2329784 | 0.77 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL8389316 | 0.76 | MAPK14 (0.64) | MAPK14PTGS2PTGS1 | |
| SCHEMBL5694270 | 0.74 | MAPK14 (0.62) | MAPK14PTGS2PTGS1 | |
| SCHEMBL5083262 | 0.74 | MAPK14 (0.57) | MAPK14PTGS2PTGS1 | |
| SCHEMBL8654831 | 0.74 | PTGS2 (0.60) | MAPK14PTGS2PTGS1 | |
| SCHEMBL21346789 | 0.74 | MAPK14 (0.52) | MAPK14PTGS2PTGS1 | |
| SCHEMBL16434857 | 0.72 | HTR2A (0.41) | MAPK14PTGS2PTGS1 | |
| Hydrochloric Acid SCHEMBL16422861 | 0.71 | HTR2A (0.40) | MAPK14PTGS2PTGS1 | |
| SCHEMBL6024005 | 0.71 | PTGS2 (0.70) | MAPK14PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841729-A1 | 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA | Amorepacific Corporation (KR) | 2007-10-10 | — | — | EP | claimed |
| WO-2006059867-A1 | 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA | AMOREPACIFIC CORPORATION (KR) | 2006-06-08 | — | — | WO | claimed |