Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | IDO1 | P14902 | 1/20 | 0.64 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | AGXT | P21549 | 1/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17760435 | 0.81 | AOC3 (0.54) | THRBIDO1AOC3FFAR1FFAR4 | |
| SCHEMBL22000113 | 0.81 | BCHE (0.55) | AOC3FFAR1FFAR4KDM1AMAOA | |
| SCHEMBL5551654 | 0.80 | THRB (0.73) | THRBIDO1FFAR1FFAR4ALDH1A1 | |
| SCHEMBL208455 | 0.79 | — | — | |
| SCHEMBL18664427 | 0.79 | AOC3 (0.53) | AOC3FFAR1FFAR4KDM1AMAOA | |
| SCHEMBL6895474 | 0.79 | AOC3 (0.53) | AOC3FFAR1FFAR4KDM1AMAOA | |
| SCHEMBL6895476 | 0.79 | AOC3 (0.53) | AOC3FFAR1FFAR4KDM1AMAOA | |
| SCHEMBL21507984 | 0.79 | AOC3 (0.53) | AOC3FFAR1FFAR4KDM1AMAOA | |
| SCHEMBL17251747 | 0.79 | IDO1 (0.64) | IDO1AOC3FFAR1FFAR4KDM1A | |
| SCHEMBL1252083 | 0.79 | PRMT6 (0.73) | AOC3FFAR1FFAR4KDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1830858-A2 | 3, 6-BICYCLOLIDES | Enanta Pharmaceuticals, Inc. (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006063039-A2 | 3, 6-BICYCLOLIDES | ENANTA PHARMACEUTICALS, INC. (US) | 2006-06-15 | — | — | WO | disclosed |