Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 4/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5550712 | 1.00 | TTR (0.51) | TTRBACE1PTGS2PTGS1MAPT | |
| SCHEMBL6906382 | 0.89 | KMT2A (0.53) | TTRMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL6906384 | 0.89 | KMT2A (0.53) | TTRMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL16982147 | 0.79 | CA12 (0.56) | BACE1PTGS2PTGS1MAPTALDH1A1 | |
| SCHEMBL4655499 | 0.77 | TTR (0.49) | TTRMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL27462458 | 0.77 | LMNA (0.54) | TTRPTGS2PTGS1MAPTKMT2A | |
| SCHEMBL9522627 | 0.76 | CYP19A1 (0.55) | PTGS2MAPTKMT2ANPSR1MEN1 | |
| SCHEMBL9522624 | 0.76 | CYP19A1 (0.55) | PTGS2MAPTKMT2ANPSR1MEN1 | |
| SCHEMBL5315888 | 0.75 | MAOB (0.61) | PTGS2PTGS1MAPTKMT2AMEN1 | |
| SCHEMBL9523424 | 0.75 | MAOB (0.61) | PTGS2PTGS1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084269-B1 | NOVEL PEROXIDASE SUBSTRATES AND THEIR USE IN CATALYZED REPORTER DEPOSITION | PERKINELMER LAS INC (US) | 2007-04-25 | — | — | EP | disclosed |