Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.49 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24620635 | 0.90 | MAPT (0.39) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24620659 | 0.83 | MAPT (0.47) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL25954142 | 0.83 | MAPT (0.47) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28370082 | 0.81 | LMNA (0.51) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL162513 | 0.81 | LMNA (0.51) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20643563 | 0.78 | MAPT (0.44) | MAPTALDH1A1RAB9ANPC1TP53 | |
| SCHEMBL10018215 | 0.77 | TP53 (0.50) | MAPTALDH1A1RAB9ANPC1TP53 | |
| SCHEMBL1962637 | 0.77 | AKR1C3 (0.49) | MAPTALDH1A1SMN1; SMN2TP53HPGD | |
| SCHEMBL13452265 | 0.76 | ESR1 (0.36) | MAPTALDH1A1SMN1; SMN2TP53HPGD | |
| SCHEMBL25954140 | 0.76 | KMT2A (0.41) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975619-B1 | INTENSE COLOURING PHOTOCHROMIC 2H-NAPHTHO[1,2-b] PYRANS AND HETEROCYCLIC PYRANS | JAMES ROBINSON LTD (GB) | 2007-01-03 | — | — | EP | disclosed |