Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.73 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6791438 | 0.90 | KDM4E (0.77) | KDM4EHTTPKMSMN1; SMN2MEN1 | |
| SCHEMBL6791434 | 0.90 | KDM4E (0.77) | KDM4EHTTPKMSMN1; SMN2MEN1 | |
| SCHEMBL14697252 | 0.85 | KDM4E (0.70) | KDM4EHTTPKMSMN1; SMN2MEN1 | |
| SCHEMBL9458519 | 0.85 | HTT (0.89) | KDM4EHTTPKMSMN1; SMN2MEN1 | |
| Bromide SCHEMBL9458813 | 0.84 | HTT (0.87) | KDM4EHTTPKMSMN1; SMN2MEN1 | |
| Bromide SCHEMBL9458818 | 0.84 | HTT (0.87) | KDM4EHTTPKMSMN1; SMN2MEN1 | |
| SCHEMBL23182183 | 0.82 | KDM4E (0.70) | KDM4EHTTPKMSMN1; SMN2MEN1 | |
| SCHEMBL4512048 | 0.82 | KDM4E (0.70) | KDM4EHTTPKMSMN1; SMN2MEN1 | |
| SCHEMBL18125935 | 0.82 | ALDH1A1 (0.71) | KDM4EHTTPKMSMN1; SMN2MEN1 | |
| SCHEMBL3844177 | 0.82 | ALDH1A1 (0.71) | KDM4EHTTPKMSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820204-A | Preparation method of R-3-benzyl-3-piperidine formyl trimethylhydrazine | 山东百诺医药股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| EP-1768976-A1 | CRYSTAL FORMS OF (3R)-1-(2-METHYLALANYL-D-TRYPTOPHYL)-3-(PHENYLMETHYL)-3-PIPERIDINECARBOXYLIC ACID 1,2,2-TRIMETHYLHYDRAZIDE | Sapphire Therapeutics, Inc. (US) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006016995-A1 | CRYSTAL FORMS OF (3R)-1-(2-METHYLALANYL-D-TRYPTOPHYL)-3-(PHENYLMETHYL)-3-PIPERIDINECARBOXYLIC ACID 1,2,2-TRIMETHYLHYDRAZIDE | SAPPHIRE THERAPEUTICS, INC. (US) | 2006-02-16 | — | — | WO | disclosed |