Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.77 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6791434 | 1.00 | KDM4E (0.77) | KDM4EHTTPKMSMN1; SMN2MEN1 | |
| SCHEMBL12009956 | 0.92 | KDM4E (0.64) | KDM4EHTTPKMSMN1; SMN2MEN1 | |
| SCHEMBL5551098 | 0.90 | KDM4E (0.73) | KDM4EHTTPKMSMN1; SMN2MEN1 | |
| SCHEMBL14697252 | 0.87 | KDM4E (0.70) | KDM4EHTTPKMSMN1; SMN2MEN1 | |
| SCHEMBL9458519 | 0.87 | HTT (0.89) | KDM4EHTTPKMSMN1; SMN2MEN1 | |
| Bromide SCHEMBL9458818 | 0.86 | HTT (0.87) | KDM4EHTTPKMSMN1; SMN2MEN1 | |
| Bromide SCHEMBL9458813 | 0.86 | HTT (0.87) | KDM4EHTTPKMSMN1; SMN2MEN1 | |
| SCHEMBL23182183 | 0.85 | KDM4E (0.70) | KDM4EHTTPKMSMN1; SMN2MEN1 | |
| SCHEMBL4512048 | 0.85 | KDM4E (0.70) | KDM4EHTTPKMSMN1; SMN2MEN1 | |
| SCHEMBL18125935 | 0.84 | ALDH1A1 (0.71) | KDM4EHTTPKMSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040039206-A1 | Process for resolving racemic mixtures of piperidine derivatives | MOHER ERIC DAVID (US) | 2004-02-26 | — | — | US | disclosed |
| US-6664271-B1 | Amide, carbamate and uredo derivatives of 3-piperidine-carboxylic acid or ester; protecting against infection by such as escherichia coli and/or actinobacillus pleuropneumoniae | ELI LILLY AND COMPANY | 2003-12-16 | — | — | US | disclosed |
| EP-1341762-A1 | PROCESS FOR RESOLVING RACEMIC MIXTURES OF PIPERIDINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002068391-A1 | PROCESS FOR RESOLVING RACEMIC MIXTURES OF PIPERIDINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039206-A1 | Process for resolving racemic mixtures of piperidine derivatives | SRR, OPRM1, SRM | KDM4E 4060/4885HTT 3257/4885PKM 3192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.