SCHEMBL5551209

SCHEMBL5551209

Cc1cccc(-c2ccc(C)cc2C)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.48
MAOB P27338 1/20 0.46
ESR2 Q92731 2/20 0.45
CNR2 P34972 2/20 0.45
CNR1 P21554 1/20 0.45
FFAR1 O14842 1/20 0.43
RAB9A P51151 3/20 0.42
ESR1 P03372 1/20 0.42
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
MAPT P10636 3/20 0.41
NPC1 O15118 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
PGR P06401 1/20 0.41
CHEK1 O14757 1/20 0.41
MAP4K4 O95819 1/20 0.41
ABL1 P00519 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30196173 0.93 ESR2 (0.47) ACHEMAOBESR2CNR2CNR1
SCHEMBL3285155 0.84 ESR2 (0.63) MAOBESR2RAB9AMAPTNPC1
SCHEMBL29865431 0.84 ALDH1A1 (0.54) MAOBESR2FFAR1RAB9AMAPT
SCHEMBL20869083 0.84 MAPT (0.41) ACHEMAOBESR2CNR2CNR1
SCHEMBL14850868 0.84 ACHE (0.54) ACHEESR2FFAR1RAB9AESR1
SCHEMBL23446825 0.84 ALDH1A1 (0.54) MAOBESR2FFAR1RAB9AMAPT
SCHEMBL15344231 0.84 ACHE (0.54) ACHEMAOBESR2CNR2CNR1
SCHEMBL20999788 0.84 MAOB (0.51) ACHEMAOBESR2RAB9AMAPT
SCHEMBL19209430 0.84 ESR2 (0.69) ACHEESR2CNR2CNR1ESR1
SCHEMBL18308794 0.82 MAPT (0.39) ACHEMAOBESR2CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7295802-B2 Image forming apparatus using a cleaning unit for preventing noises RICOH COMPANY, LTD (JP) 2007-11-13 US disclosed
US-20070110488-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDE THEREFOR KABATA TOSHIYUKI 2007-05-17 US disclosed
US-7181156-B2 Image forming apparatus using a cleaning member for preventing noises and process cartridge therefor RICOH COMPANY, LTD. (JP) 2007-02-20 US disclosed
US-20050069357-A1 Image forming apparatus and process cartridge therefor RICOH COMPANY, LTD (JP) 2005-03-31 US disclosed
US-5561016-A HAVING PHOTOCONDUCTIVE LAYER CONTAINING CHARGE GENERATING MATERIAL, POLYVINYL BUTYRAL BINDER, CHARGE TRANSPORTING MATERIAL AND BIPHENYL(OR DERIVATIVE) ON ELECTROCONDUCTIVE SUPPORT RICOH COMPANY, LTD. (JP) 1996-10-01 US disclosed
US-4182915-A PHENOL FROM BENZENE BY REACTION OF THALLIUM/III/ METALLATE WITH HYDROXYL DONOR HALCON INTERNATIONAL, INC. (US) 1980-01-08 US disclosed