Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15062421 | 0.86 | TUBB1 (0.30) | AKR1C3AKR1C2TUBB1 | |
| SCHEMBL15062727 | 0.85 | — | — | |
| SCHEMBL15062452 | 0.83 | TUBB1 (0.30) | TUBB1 | |
| SCHEMBL2004628 | 0.82 | AKR1C3 (0.48) | AKR1C3AKR1C2TSHRLMNAKMT2A | |
| SCHEMBL5798176 | 0.81 | CYP1A2 (0.41) | AKR1C3AKR1C2TSHRLMNAKMT2A | |
| SCHEMBL5800598 | 0.81 | AKR1C3 (0.43) | AKR1C3AKR1C2TSHRLMNAKMT2A | |
| SCHEMBL15062672 | 0.76 | TP53 (0.31) | — | |
| SCHEMBL15062604 | 0.75 | — | — | |
| SCHEMBL27889075 | 0.75 | TP53 (0.32) | AKR1C3AKR1C2TUBB1LMNAKMT2A | |
| SCHEMBL15062633 | 0.75 | CYP2C9 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070203209-A1 | Useful indole compounds | IRONWOOD PHARMACEUTICALS, INC. | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203209-A1 | Useful indole compounds | TPH2, HRH2, HRH1 | AKR1C3 1451/4885AKR1C2 1219/4885TUBB1 1583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.