Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800598 | 0.91 | AKR1C3 (0.43) | LMNATSHRMAPTALDH1A1GAA | |
| SCHEMBL5551297 | 0.81 | AKR1C3 (0.33) | LMNATSHRKMT2AAKR1C3AKR1C2 | |
| SCHEMBL5549756 | 0.80 | LMNA (0.59) | CYP1A2LMNANPSR1TSHRCYP2D6 | |
| SCHEMBL6424196 | 0.79 | PTGS1 (0.41) | CYP1A2LMNANPSR1TSHRCYP2D6 | |
| SCHEMBL15062421 | 0.79 | TUBB1 (0.30) | AKR1C3AKR1C2 | |
| SCHEMBL15062452 | 0.79 | TUBB1 (0.30) | — | |
| SCHEMBL15062727 | 0.77 | — | — | |
| SCHEMBL6426732 | 0.76 | NPSR1 (0.41) | CYP1A2LMNANPSR1TSHRCYP2D6 | |
| SCHEMBL6424056 | 0.76 | LMNA (0.39) | CYP1A2LMNANPSR1TSHRCYP2D6 | |
| SCHEMBL15062633 | 0.76 | CYP2C9 (0.31) | CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |