SCHEMBL5551757

SCHEMBL5551757

O=C(c1cc2ccccc2cc1O)N(Cl)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.47
▸ MEN1 O00255 3/20 0.47
▸ KMT2A Q03164 3/20 0.47
▸ GAA P10253 3/20 0.47
▸ TDP1 Q9NUW8 2/20 0.47
▸ MITF O75030 1/20 0.47
▸ NCOA1 Q15788 1/20 0.47
▸ NCOA3 Q9Y6Q9 1/20 0.47
▸ KDM4E B2RXH2 3/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ CASP1 P29466 1/20 0.43
▸ CASP7 P55210 1/20 0.43
▸ NPC1 O15118 3/20 0.41
▸ RAB9A P51151 2/20 0.41
▸ POLB P06746 1/20 0.41
▸ MAPK1 P28482 2/20 0.40
▸ LMNA P02545 1/20 0.40
▸ THRB P10828 1/20 0.40
▸ MMP14 P50281 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14328976 0.83 MAPT (0.50) MAPTMEN1KMT2AGAATDP1
SCHEMBL11592277 0.80 MAOB (0.58) MAPTMEN1KMT2AGAATDP1
SCHEMBL6881139 0.79 NPC1 (0.52) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL1476946 0.76 SMN1; SMN2 (0.61) MAPTMEN1KMT2AGAATDP1
SCHEMBL27704241 0.76 MAPT (0.51) MAPTMEN1KMT2AGAATDP1
SCHEMBL8662764 0.76 HPGD (0.47) MAPTMEN1KMT2AGAATDP1
SCHEMBL6697937 0.76 GRIN2D (0.63) MAPTMEN1KMT2AGAATDP1
SCHEMBL6697931 0.76 GRIN2D (0.63) MAPTMEN1KMT2AGAATDP1
SCHEMBL10938954 0.75 RAB9A (0.58) MAPTMEN1KMT2AGAATDP1
SCHEMBL11592381 0.74 KMT2A (0.45) MAPTMEN1KMT2AGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7175958-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same RICOH COMPANY, LTD. (JP) 2007-02-13 — — US disclosed
US-20050112487-A1 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same SHOSHI MASAYUKI (JP) 2005-05-26 — — US disclosed
US-6849367-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and a process cartridge for the same RICOH COMPANY, LTD. (JP) 2005-02-01 — — US disclosed
US-20030190540-A1 Electrophotographic photoconductor, process for forming an image, image forming apparatus and a process cartridge for the same RICOH COMPANY, LTD. (JP) 2003-10-09 — — US disclosed
Send feedback