Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16735595 | 0.85 | MET (0.54) | SMN1; SMN2NPC1RAB9ATP53KMT2A | |
| SCHEMBL27704241 | 0.85 | MAPT (0.51) | SMN1; SMN2NPC1RAB9ATP53KMT2A | |
| SCHEMBL23640265 | 0.81 | HSP90AA1 (0.54) | SMN1; SMN2NPC1RAB9AKMT2AHPGD | |
| SCHEMBL12521449 | 0.80 | SIGMAR1 (0.51) | SMN1; SMN2NPC1RAB9ATP53KMT2A | |
| SCHEMBL21644524 | 0.80 | CYP3A4 (0.74) | SMN1; SMN2NPC1RAB9ATP53TSHR | |
| SCHEMBL11592277 | 0.80 | MAOB (0.58) | KMT2AKDM4EPDK1MEN1MAPT | |
| SCHEMBL14328976 | 0.79 | MAPT (0.50) | NPC1RAB9AKMT2AMAPK1KDM4E | |
| SCHEMBL11683390 | 0.78 | KMT2A (0.46) | SMN1; SMN2NPC1RAB9AKMT2AHPGD | |
| SCHEMBL6430222 | 0.77 | MEN1 (0.63) | SMN1; SMN2NPC1RAB9ATP53KMT2A | |
| SCHEMBL20369015 | 0.77 | MEN1 (0.59) | SMN1; SMN2NPC1RAB9ATP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172311-A1 | Compounds For Treating Human Papillomavirus | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-07-14 | — | — | US | disclosed |
| US-20110172311-A1 | Compounds For Treating Human Papillomavirus | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-07-14 | — | — | US | disclosed |
| US-20110172311-A1 | Compounds For Treating Human Papillomavirus | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-07-14 | — | — | US | disclosed |
| US-7914769-B2 | Compounds for treating human papillomavirus | UNIVERSITY OF MASSACHUSETTS (US) | 2011-03-29 | — | — | US | disclosed |
| US-7914769-B2 | Compounds for treating human papillomavirus | UNIVERSITY OF MASSACHUSETTS (US) | 2011-03-29 | — | — | US | disclosed |
| US-7914769-B2 | Compounds for treating human papillomavirus | UNIVERSITY OF MASSACHUSETTS (US) | 2011-03-29 | — | — | US | disclosed |
| WO-2005110391-A2 | COMPOUNDS FOR TREATING HUMAN PAPILLOMAVIRUS | UNIVERSITY OF MASSACHUSETTS (US) | 2005-11-24 | — | — | WO | disclosed |
| US-20050250855-A1 | Compounds for treating human papillomavirus | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250855-A1 | Compounds for treating human papillomavirus | TP53, POLI, CDC73 | SMN1; SMN2 2535/4885NPC1 1501/4885RAB9A 4207/4885 |
| US-20110172311-A1 | Compounds For Treating Human Papillomavirus | TP53, POLI, CDC73 | SMN1; SMN2 2535/4885NPC1 1501/4885RAB9A 4207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.