Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726066 | 0.78 | TSHR (0.33) | TSHR | |
| Hydrochloric Acid SCHEMBL9725931 | 0.77 | TSHR (0.32) | TSHR | |
| Hydrochloric Acid SCHEMBL9726062 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL9588054 | 0.72 | CES2 (0.31) | CES2 | |
| Hydrochloric Acid SCHEMBL9725944 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL9725969 | 0.70 | GAA (0.30) | — | |
| Hydrochloric Acid SCHEMBL9725859 | 0.66 | TAS2R14 (0.31) | — | |
| SCHEMBL1006516 | 0.64 | — | — | |
| SCHEMBL9030346 | 0.63 | CYP1A2 (0.35) | ALDH1A1CYP1A2 | |
| SCHEMBL25180726 | 0.61 | SMN1; SMN2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796751-A2 | TRANSGLUTAMINASE CROSSLINKED COLLAGEN BIOMATERIAL FOR MEDICAL IMPLANT MATERIALS | Aston University (GB) | 2007-06-20 | — | — | EP | disclosed |
| EP-1648924-A2 | DIPEPTIDE TRANSGLUTAMINASE INHIBITORS AND METHODS OF USING THE SAME | The Nottingham Trent University (GB) | 2006-04-26 | — | — | EP | disclosed |
| WO-2006027622-A2 | TRANSGLUTAMINASE CROSSLINKED COLLAGEN BIOMATERIAL FOR MEDICAL IMPLANT MATERIALS | ASTON UNIVERSITY (GB) | 2006-03-16 | — | — | WO | disclosed |
| WO-2004113363-A2 | DIPEPTIDE TRANSGLUTAMINASE INHIBITORS AND METHODS OF USING THE SAME | THE NOTTINGHAM TRENT UNIVERSITY (GB) | 2004-12-29 | — | — | WO | disclosed |