SCHEMBL5551808

SCHEMBL5551808

COc1ccc2cc(-c3c4ccccc4c(Br)c4ccccc34)ccc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.52
CYP2A6 P11509 1/20 0.52
CYP11B2 P19099 7/20 0.51
CYP11B1 P15538 6/20 0.51
CYP3A4 P08684 2/20 0.51
CYP2C9 P11712 2/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2B6 P20813 1/20 0.51
CYP2C19 P33261 1/20 0.51
HSD17B1 P14061 1/20 0.50
HSD17B2 P37059 1/20 0.50
GSTP1 P09211 1/20 0.47
NPC1 O15118 5/20 0.46
RAB9A P51151 5/20 0.46
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPT P10636 2/20 0.46
HPGD P15428 2/20 0.46
LMNA P02545 1/20 0.46
NFKB1 P19838 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1041430 0.92 CYP1A2 (0.61) CYP1A2CYP2A6CYP11B2CYP11B1CYP3A4
SCHEMBL14233923 0.90 CYP1A2 (0.59) CYP1A2CYP2A6CYP11B2CYP11B1CYP3A4
SCHEMBL13015667 0.87 CYP11B2 (0.58) CYP1A2CYP2A6CYP11B2CYP11B1CYP3A4
SCHEMBL5551754 0.84 ACHE (0.53) KDM4EALDH1A1MAPTHPGDLMNA
SCHEMBL27872144 0.84 CYP1A2 (0.56) CYP1A2CYP2A6CYP11B2CYP11B1CYP3A4
SCHEMBL10030011 0.84 CYP1A2 (0.52) CYP1A2CYP2A6CYP11B2CYP11B1CYP3A4
SCHEMBL27862687 0.83 CYP1A2 (0.60) CYP1A2CYP2A6CYP11B2CYP11B1CYP3A4
SCHEMBL12926845 0.83 CYP11B2 (0.48) CYP1A2CYP2A6CYP11B2CYP11B1CYP3A4
SCHEMBL31347846 0.83 CYP2A6 (0.45) CYP1A2CYP2A6CYP11B2CYP11B1HSD17B1
SCHEMBL22042806 0.83 CYP2A6 (0.45) CYP1A2CYP2A6CYP11B2CYP11B1HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221434-B1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEMICALS INC (JP) 2012-06-27 EP disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed
US-20050074631-A1 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2005-04-07 US disclosed