Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | PNMT | P11086 | 2/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | SCN4A | P35499 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282596 | 0.89 | PNMT (0.53) | SLC6A2SLC6A3SLC6A4PNMTOPRM1 | |
| SCHEMBL1157274 | 0.85 | PNMT (0.45) | SLC6A2SLC6A3SLC6A4PNMTGBA1 | |
| SCHEMBL6442526 | 0.83 | SLC6A4 (0.57) | SLC6A2SLC6A3SLC6A4TACR1SCN4A | |
| SCHEMBL3282306 | 0.80 | PNMT (0.56) | SLC6A2SLC6A3SLC6A4PNMTOPRM1 | |
| SCHEMBL200500 | 0.80 | SLC6A2 (0.56) | SLC6A2SLC6A3SLC6A4PNMTSLC2A1 | |
| SCHEMBL14830680 | 0.80 | SLC2A1 (0.57) | SLC6A2SLC6A3SLC2A1 | |
| Hydrochloric Acid SCHEMBL3372120 | 0.79 | SLC6A2 (0.54) | SLC6A2SLC6A3SLC6A4PNMTSLC2A1 | |
| SCHEMBL949577 | 0.79 | PNMT (0.62) | SLC6A2SLC6A4PNMTTAAR1TACR1 | |
| SCHEMBL5703577 | 0.78 | HTR2A (0.47) | SLC6A2SLC6A3SLC6A4SCN4A | |
| SCHEMBL3617955 | 0.77 | GBA1 (0.48) | PNMTOPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807388-A2 | ACYCLIC HYDRAZIDES AS CANNABINOID RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006041797-A2 | ACYCLIC HYDRAZIDES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2006-04-20 | — | — | WO | disclosed |