Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.62 |
| ▸ | TACR1 | P25103 | 3/20 | 0.54 |
| ▸ | IDO1 | P14902 | 3/20 | 0.51 |
| ▸ | TDO2 | P48775 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | SCN4A | P35499 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282596 | 0.89 | PNMT (0.53) | PNMTTACR1IDO1TDO2SLC6A2 | |
| SCHEMBL272604 | 0.80 | EPHX1 (0.61) | SLC6A2SLC6A4SIGMAR1TAAR1GRIN2B | |
| SCHEMBL3451169 | 0.80 | EPHX1 (0.61) | SLC6A2SLC6A4SIGMAR1TAAR1GRIN2B | |
| SCHEMBL468022 | 0.80 | EPHX1 (0.61) | SLC6A2SLC6A4SIGMAR1TAAR1GRIN2B | |
| SCHEMBL4986022 | 0.80 | TACR1 (0.77) | TACR1IDO1TDO2CYP3A4AGXT | |
| SCHEMBL3282306 | 0.80 | PNMT (0.56) | PNMTTACR1IDO1SLC6A2SLC6A4 | |
| SCHEMBL23655308 | 0.80 | AGXT (0.50) | SLC6A2SLC6A4SIGMAR1TAAR1AGXT | |
| SCHEMBL17196630 | 0.80 | MAOA (0.55) | TACR1SLC6A2SLC6A4SIGMAR1TAAR1 | |
| SCHEMBL25517567 | 0.80 | LMNA (0.65) | PNMTTACR1IDO1TDO2SLC6A2 | |
| SCHEMBL1570196 | 0.79 | PNMT (0.69) | PNMTTACR1IDO1TAAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713786-B1 | 1-(AZOLIN-2-YL) AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATTING INSECTS, ARACHNIDS AND NEMATODES | BASF SE (DE) | 2012-08-08 | — | — | EP | disclosed |
| US-7871960-B2 | 1-(Imidazolin-2-yl)amino-1,2-diphenylethane compounds for combating animal pests | BASF SE (DE) | 2011-01-18 | — | — | US | disclosed |
| EP-1888533-B1 | 1-(IMIDAZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2010-12-15 | — | — | EP | disclosed |
| US-7655600-B2 | 4,5-Dihydro-4-methyloxazol-2-yl)-[2-(3-chloro-phenyl)-1-phenyl-ethyl]-amine; 1-[1-(4-Chlorophenyl)-2-phenyl-ethyl]-(4,5-dihydrothiazol-2-yl)-amine; animal pests; agriculture; broad activity spectrum against difficult to control insects etc. | BASF AKTIENGESELLSCHAFT (DE) | 2010-02-02 | — | — | US | disclosed |
| CN-100572367-C | 1- (azolin-2-yl) amino-1, 2-diphenylethane compounds for controlling insects, arachnids and nematodes | BASF AG (DE) | 2009-12-23 | — | — | CN | disclosed |
| CN-100566712-C | Polyamine compounds for the treatment of chemokine receptor mediated diseases | TAIGEN BIOTECHNOLOGY CO LTD (CN) | 2009-12-09 | — | — | CN | disclosed |
| US-20080200335-A1 | 1-(Imidazolin-2-Yl)Amino-1,2-Diphenylethane Compounds For Combating Animal Pests | BASF AKTIENGESELLSCHAFT (DE) | 2008-08-21 | — | — | US | disclosed |
| EP-1888533-A1 | 1-(IMIDAZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-20 | — | — | EP | disclosed |
| US-20070149582-A1 | 1-(Azolin-2-yl)amino-1,2-diphenylethane compounds for combating insects, arachnids and nematodes | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-28 | — | — | US | disclosed |
| CN-1898218-A | 1-(azolin-2-yl)amino-1,2-diphenylethane compounds for combatting insects, arachnids and nematodes | BASF AG (DE) | 2007-01-17 | — | — | CN | disclosed |
| WO-2006125748-A1 | 1-(IMIDAZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-30 | — | — | WO | disclosed |
| EP-1713786-A1 | 1-(AZOLIN-2-YL) AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATTING INSECTS, ARACHNIDS AND NEMATODES | BASF AKTIENGESELLSCHAFT (DE) | 2006-10-25 | — | — | EP | disclosed |
| CN-1798551-A | Polyamine compounds for the treatment of chemokine receptor mediated diseases | TAIGEN BIOTECHNOLOGY CO LTD (CN) | 2006-07-05 | — | — | CN | disclosed |
| WO-2005063724-A1 | 1-(AZOLIN-2-YL) AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATTING INSECTS, ARACHNIDS AND NEMATODES | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149582-A1 | 1-(Azolin-2-yl)amino-1,2-diphenylethane compounds for combating insects, arachnids and nematodes | ANXA1, ANTXR2, ANXA2 | PNMT 784/4885TACR1 503/4885IDO1 9/4885 |
| US-20080200335-A1 | 1-(Imidazolin-2-Yl)Amino-1,2-Diphenylethane Compounds For Combating Animal Pests | ANXA1, ANXA11, AGO2 | PNMT 601/4885TACR1 4731/4885IDO1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.