Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | RBP4 | P02753 | 10/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | SORD | Q00796 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5559566 | 0.87 | KDM4E (0.58) | RBP4KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL5558108 | 0.85 | ALDH1A1 (0.43) | RBP4KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL5558124 | 0.83 | ALDH1A1 (0.45) | RBP4KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL10266109 | 0.81 | KDM4E (0.49) | KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL5525363 | 0.79 | HRH4 (0.46) | HRH4RBP4KDM4EHPGDHSD17B10 | |
| SCHEMBL10266309 | 0.71 | GBA1 (0.44) | KDM4EHPGDHSD17B10ALDH1A1SORD | |
| SCHEMBL27680981 | 0.70 | KDM4E (0.60) | RBP4KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL25312133 | 0.69 | RBP4 (0.80) | RBP4TTR | |
| SCHEMBL27681034 | 0.69 | RBP4 (0.56) | RBP4KDM4EHPGDHSD17B10USP2 | |
| Hydrochloric Acid SCHEMBL3281689 | 0.69 | IKBKB (0.44) | HRH4KDM4EP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | HRH4 3167/4885RBP4 3571/4885KDM4E 676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.