Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 19/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5555108 | 1.00 | P2RX7 (0.61) | P2RX7 | |
| SCHEMBL4128412 | 0.85 | P2RX7 (0.66) | P2RX7 | |
| SCHEMBL5549843 | 0.85 | P2RX7 (0.67) | P2RX7 | |
| SCHEMBL5549326 | 0.85 | P2RX7 (0.67) | P2RX7 | |
| SCHEMBL5555101 | 0.84 | P2RX7 (0.82) | P2RX7 | |
| SCHEMBL5553043 | 0.84 | P2RX7 (0.82) | P2RX7 | |
| SCHEMBL5549346 | 0.83 | P2RX7 (0.67) | P2RX7 | |
| SCHEMBL14497213 | 0.83 | P2RX7 (0.67) | P2RX7 | |
| SCHEMBL5553039 | 0.83 | P2RX7 (0.67) | P2RX7 | |
| SCHEMBL4122066 | 0.81 | P2RX7 (0.60) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7227038-B2 | Adamantane derivatives, processes for their preparation and pharmaceutical composition containing them | ASTRAZENECA AB (SE) | 2007-06-05 | — | — | US | disclosed |
| US-20060160904-A1 | Adamantane derivatives, processes for their preparation and pharmaceutical composition containing them | ASTRAZENECA AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160904-A1 | Adamantane derivatives, processes for their preparation and pharmaceutical composition containing them | BACE1, ADORA1, ADRA1D | P2RX7 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.