SCHEMBL5553183

SCHEMBL5553183

NC(=O)c1cc(-c2ccccc2O)cc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.46
ALDH1A1 P00352 3/20 0.46
GAA P10253 2/20 0.46
HPGD P15428 2/20 0.46
HSD17B10 Q99714 2/20 0.46
MAPT P10636 2/20 0.46
TSHR P16473 1/20 0.46
ACMSD Q8TDX5 2/20 0.46
MCL1 Q07820 1/20 0.46
IKBKB O14920 3/20 0.44
HTT P42858 1/20 0.43
ESR2 Q92731 1/20 0.42
BCAT2 O15382 1/20 0.42
HTR2B P41595 1/20 0.41
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
BCL2L1 Q07817 1/20 0.40
LCK P06239 1/20 0.40
CHUK O15111 1/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5014949 0.85 KDM4E (0.55) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL11868722 0.80 HSD17B10 (0.50) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL21409661 0.78 HSD17B1 (0.53) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL8797558 0.76 CDC25B (0.60) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL28799527 0.75 KDM4E (0.53) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL27539934 0.73 ESR2 (0.47) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL28191116 0.73 CYP1A2 (0.55) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL7518100 0.73 KDM4E (0.55) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL27668833 0.72 KDM4E (0.67) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL30350972 0.72 KDM4E (0.67) KDM4EALDH1A1GAAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7175958-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same RICOH COMPANY, LTD. (JP) 2007-02-13 US disclosed
US-20050112487-A1 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same SHOSHI MASAYUKI (JP) 2005-05-26 US disclosed
US-6849367-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and a process cartridge for the same RICOH COMPANY, LTD. (JP) 2005-02-01 US disclosed
US-20030190540-A1 Electrophotographic photoconductor, process for forming an image, image forming apparatus and a process cartridge for the same RICOH COMPANY, LTD. (JP) 2003-10-09 US disclosed
US-4871633-A PHOTOELECTRICAL CHARGE GENERATING COMPOUND MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-10-03 US disclosed