Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HSD17B1 | P14061 | 7/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 7/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5553183 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1GAAHSD17B1HSD17B2 | |
| SCHEMBL634882 | 0.84 | KDM4E (0.65) | KDM4EALDH1A1GAAHSD17B1HSD17B2 | |
| SCHEMBL5023244 | 0.81 | PARP1 (0.50) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL5016686 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL2381295 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1GAAPARP1KDR | |
| SCHEMBL27582824 | 0.76 | ESR2 (0.62) | ALDH1A1HSD17B1HSD17B2ESR2HPGD | |
| SCHEMBL1807859 | 0.76 | KDM4E (0.62) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL634716 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1GAAHSD17B1HSD17B2 | |
| SCHEMBL31621279 | 0.74 | SLC6A2 (0.64) | KDM4EALDH1A1GAAESR2HPGD | |
| SCHEMBL21071005 | 0.74 | HSD17B1 (0.76) | ALDH1A1HSD17B1HSD17B2ESR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449608-B2 | Naphthol derivative and charge control agent comprising the same | UENO FINE CHEMICALS INDUSTRY, LTD. (JP) | 2008-11-11 | — | — | US | disclosed |
| US-20050119487-A1 | Naphthol derivative and charge control agent comprising the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2005-06-02 | — | — | US | disclosed |
| EP-1462440-A1 | NAPHTHOL DERIVATIVE AND CHARGE CONTROL AGENT COMPRISING THE SAME | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 2004-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119487-A1 | Naphthol derivative and charge control agent comprising the same | CECR2, PEF1, NAP1L1 | KDM4E 2651/4885ALDH1A1 3851/4885GAA 1045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.