Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779970 | 0.83 | — | — | |
| SCHEMBL701411 | 0.74 | ALDH1A1 (0.53) | ALDH1A1FAAH | |
| SCHEMBL30831434 | 0.74 | ALDH1A1 (0.53) | ALDH1A1FAAH | |
| Hydrochloric Acid SCHEMBL9433989 | 0.73 | ALDH1A1 (0.51) | ALDH1A1FAAH | |
| SCHEMBL22502032 | 0.73 | DYRK1A (0.36) | ALDH1A1 | |
| SCHEMBL3802754 | 0.73 | CYP1A2 (0.55) | ALDH1A1 | |
| SCHEMBL5777247 | 0.73 | PDGFRB (0.34) | — | |
| Bromide SCHEMBL9399281 | 0.73 | ALDH1A1 (0.51) | ALDH1A1FAAH | |
| SCHEMBL5779540 | 0.73 | PDGFRB (0.33) | — | |
| SCHEMBL1738967 | 0.71 | CA2 (0.41) | HSD17B10RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076104-A1 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2007-07-05 | — | — | WO | disclosed |
| EP-1780211-A2 | Vanilloid receptor ligands and their use in treatments | Amgen Inc. (US) | 2007-05-02 | — | — | EP | disclosed |
| EP-1775295-A1 | Vanilloid receptor ligands and their use in treatments | Amgen Inc. (US) | 2007-04-18 | — | — | EP | disclosed |