Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 18/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067249 | 0.75 | NOS2 (0.57) | NOS2MAOAMAOB | |
| SCHEMBL5203317 | 0.74 | NOS2 (0.90) | NOS2 | |
| SCHEMBL5203057 | 0.74 | NOS2 (0.90) | NOS2 | |
| SCHEMBL5203041 | 0.74 | NOS2 (0.90) | NOS2 | |
| SCHEMBL6942377 | 0.73 | NOS2 (1.00) | NOS2MAOAMAOB | |
| SCHEMBL6939204 | 0.73 | NOS2 (0.80) | NOS2MAOAMAOB | |
| SCHEMBL5201831 | 0.73 | NOS2 (1.00) | NOS2 | |
| SCHEMBL5201896 | 0.73 | NOS2 (1.00) | NOS2 | |
| SCHEMBL5202294 | 0.73 | NOS2 (1.00) | NOS2 | |
| SCHEMBL5201861 | 0.73 | NOS2 (1.00) | NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1795192-A2 | 1-Substituted imidazole derivatives as nos inhibitors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2007-06-13 | — | — | EP | disclosed |