Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 16/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27834828 | 0.84 | MAOA (0.64) | NOS2MAOAMAOBUSP2ALDH1A1 | |
| SCHEMBL21791731 | 0.81 | LMNA (0.62) | CYP1A2CYP3A4CYP2D6CYP2C19LMNA | |
| SCHEMBL6942859 | 0.78 | NOS2 (0.73) | NOS2MAOAMAOB | |
| SCHEMBL5202697 | 0.78 | NOS2 (0.58) | NOS2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL5204903 | 0.78 | NOS2 (0.58) | NOS2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL108109 | 0.77 | TAAR1 (0.62) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6946779 | 0.76 | NOS2 (0.61) | NOS2MAOAMAOB | |
| SCHEMBL6944316 | 0.76 | NOS2 (0.58) | NOS2MAOAMAOBUSP2ALDH1A1 | |
| SCHEMBL109195 | 0.75 | TAAR1 (0.64) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL5553392 | 0.75 | NOS2 (0.57) | NOS2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363628-A2 | DRUGS FOR SEX DYSFUNCTIONS | NICOX S.A. (FR) | 2003-11-26 | — | — | EP | claimed |
| WO-2002011706-A2 | DRUGS FOR SEX DYSFUNCTIONS | NICOX S.A. (FR) | 2002-02-14 | — | — | WO | claimed |