Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 5/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3241675 | 0.90 | SMYD3 (0.52) | SMYD3MAPK14 | |
| SCHEMBL5553413 | 0.84 | LMNA (0.58) | SMYD3ALDH1A1HSD17B10 | |
| SCHEMBL5559915 | 0.83 | MMP9 (0.49) | — | |
| SCHEMBL3238605 | 0.78 | SMYD3 (0.50) | SMYD3MAPK14 | |
| SCHEMBL5559054 | 0.78 | MMP9 (0.46) | — | |
| SCHEMBL3243486 | 0.77 | SMYD3 (0.68) | SMYD3MAPK14 | |
| SCHEMBL3242010 | 0.74 | PLAU (0.58) | — | |
| SCHEMBL3245686 | 0.72 | LMNA (0.68) | SMYD3MAPK14ALDH1A1HSD17B10 | |
| SCHEMBL5559022 | 0.71 | MMP9 (0.52) | — | |
| SCHEMBL3244706 | 0.70 | MMP9 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509516-B1 | INHIBITORS OF THE GPIB -VWF INTERACTION, THEIR PREPARATION AND USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-01-31 | — | — | EP | claimed |