Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 2/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.30 |
| ▸ | PIM1 | P11309 | 2/20 | 0.30 |
| ▸ | PRKACA | P17612 | 2/20 | 0.30 |
| ▸ | FLT1 | P17948 | 2/20 | 0.30 |
| ▸ | KDR | P35968 | 2/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.30 |
| ▸ | GSK3A | P49840 | 2/20 | 0.30 |
| ▸ | GSK3B | P49841 | 2/20 | 0.30 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.30 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.30 |
| ▸ | PLK4 | O00444 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20319767 | 0.72 | ALDH1A1 (0.32) | CDK8ICAM1SELEVCAM1CCNC | |
| SCHEMBL30154117 | 0.68 | CYP2A6 (0.36) | DAPK3PIM1PRKACAFLT1KDR | |
| SCHEMBL5555026 | 0.68 | ICAM1 (0.50) | PTPN2CDK8ICAM1SELEVCAM1 | |
| SCHEMBL30099336 | 0.68 | ICAM1 (0.33) | CDK8ICAM1SELEVCAM1DAPK3 | |
| SCHEMBL18105431 | 0.68 | ICAM1 (0.35) | CDK8ICAM1SELEVCAM1DAPK3 | |
| SCHEMBL30154130 | 0.67 | SLC22A12 (0.30) | — | |
| SCHEMBL7054296 | 0.67 | CDK8 (0.66) | CDK8ICAM1SELEVCAM1CCNC | |
| SCHEMBL5555035 | 0.67 | MAP3K8 (0.60) | CDK8ICAM1SELEVCAM1CCNC | |
| SCHEMBL19439609 | 0.66 | PNMT (0.38) | PTPN2 | |
| SCHEMBL5550255 | 0.66 | MAP3K8 (0.63) | CDK8ICAM1SELEVCAM1CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4373825-A1 | NITRILE SUMO INHIBITORS AND USES THEREOF | Suvalent Therapeutics, Inc. (US) | 2024-05-29 | — | — | EP | disclosed |
| WO-2023004376-A1 | NITRILE SUMO INHIBITORS AND USES THEREOF | Suvalent Therapeutics, Inc. (US) | 2023-01-26 | — | — | WO | disclosed |
| EP-1753428-A2 | KINASE INHIBITORS AS THERAPEUTIC AGENTS | Abbott Laboratories (US) | 2007-02-21 | — | — | EP | disclosed |
| US-20060074102-A1 | Kinase inhibitors as therapeutic agents | ABBOTT LABORATORIES | 2006-04-06 | — | — | US | disclosed |
| WO-2005110410-A2 | KINASE INHIBITORS AS THERAPEUTIC AGENTS | ABBOTT LABORATORIES (US) | 2005-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074102-A1 | Kinase inhibitors as therapeutic agents | ABL1, MAP3K19, MAP3K20 | PTPN2 457/4885CDK8 181/4885ICAM1 4375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.