Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5554480 | 0.82 | MAPT (0.60) | NPC1MAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL18917635 | 0.79 | NPC1 (0.68) | NPC1MAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL17681921 | 0.79 | NPC1 (0.65) | NPC1MAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL5902231 | 0.79 | NPC1 (1.00) | NPC1MAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL29414999 | 0.79 | NPC1 (1.00) | NPC1MAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL7409529 | 0.77 | MAPT (0.57) | NPC1MAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL9209028 | 0.76 | NPC1 (0.77) | NPC1MAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL6375687 | 0.76 | MAPT (0.96) | NPC1MAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL18917640 | 0.75 | NPC1 (0.61) | NPC1MAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL8137315 | 0.75 | NPC1 (0.79) | NPC1MAPTHTTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594512-A4 | COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTION | KEMIA INC (US) | 2007-07-11 | — | — | EP | claimed |
| EP-1594512-A2 | COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTION | Kemia, INC. (US) | 2005-11-16 | — | — | EP | claimed |
| US-20040248850-A1 | Compounds for the treatment of HIV infection | KEMIA, INC. | 2004-12-09 | — | — | US | claimed |
| WO-2004071426-A2 | COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTION | KEMIA INC. (US) | 2004-08-26 | — | — | WO | claimed |
| EP-1594512-A4 | COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTION | KEMIA INC (US) | 2007-07-11 | — | — | EP | disclosed |
| EP-1594512-A2 | COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTION | Kemia, INC. (US) | 2005-11-16 | — | — | EP | disclosed |
| US-20040248850-A1 | Compounds for the treatment of HIV infection | KEMIA, INC. | 2004-12-09 | — | — | US | disclosed |
| WO-2004071426-A2 | COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTION | KEMIA INC. (US) | 2004-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248850-A1 | Compounds for the treatment of HIV infection | CCR5, CD4, HAVCR2 | NPC1 29/4885MAPT 920/4885HTT 3938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.