Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 5/20 | 0.45 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808414 | 0.84 | CA1 (0.45) | CES2LMNARAB9AKMT2AMEN1 | |
| SCHEMBL20340037 | 0.84 | CA1 (0.45) | CES2LMNARAB9AKMT2AMEN1 | |
| SCHEMBL5137955 | 0.81 | TDP1 (0.48) | TDP1L3MBTL1CES1CES2LMNA | |
| SCHEMBL20340201 | 0.81 | TDP1 (0.48) | TDP1L3MBTL1CES1CES2LMNA | |
| SCHEMBL17785195 | 0.79 | TDP1 (0.47) | TDP1L3MBTL1CES1CES2LMNA | |
| SCHEMBL851629 | 0.79 | TDP1 (0.47) | TDP1L3MBTL1CES1CES2LMNA | |
| SCHEMBL15984954 | 0.79 | TDP1 (0.47) | TDP1L3MBTL1CES1CES2LMNA | |
| SCHEMBL7440566 | 0.79 | TDP1 (0.47) | TDP1L3MBTL1CES1CES2LMNA | |
| SCHEMBL10666925 | 0.78 | ATM (0.49) | TDP1L3MBTL1CES1CES2LMNA | |
| SCHEMBL11404130 | 0.78 | ATM (0.49) | TDP1L3MBTL1CES1CES2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794645-A1 | CATIONIC PEPTIDES AND USE OF SUCH PEPTIDES FOR INHIBITING EXOTOXIN PRODUCTION | Regents of the University of Minnesota (US) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013096823-A1 | CATIONIC PEPTIDES AND USE OF SUCH PEPTIDES FOR INHIBITING EXOTOXIN PRODUCTION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2013-06-27 | — | — | WO | disclosed |
| EP-1841460-A2 | THERAPEUTIC FORMULATIONS FOR THE TREATMENT OF BETA-AMYLOID RELATED DISEASES | Neurochem (International) Limited (CH) | 2007-10-10 | — | — | EP | disclosed |
| WO-2007049098-A2 | THERAPEUTIC FORMULATIONS FOR THE TREATMENT OF BETA-AMYLOID RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2007-05-03 | — | — | WO | disclosed |
| WO-2006015318-A2 | ANTIBODY CONJUGATED TO A DRUG MOIETY VIA A POPTIDIC LINKER | BIOGEN IDEC INC. (US) | 2006-02-09 | — | — | WO | disclosed |
| WO-2000011022-A1 | ANTI-CANCER COMPOUNDS AND METHODS RELATED THERETO | STEWART JOHN M (US) | 2000-03-02 | — | — | WO | disclosed |