SCHEMBL851629

SCHEMBL851629

CNC(C(=O)O)C(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CES1 P23141 4/20 0.45
CES2 O00748 3/20 0.45
LMNA P02545 2/20 0.45
TSHR P16473 3/20 0.44
TP53 P04637 1/20 0.44
ALDH1A1 P00352 4/20 0.43
HTT P42858 2/20 0.43
PGR P06401 1/20 0.43
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
HTR2A P28223 1/20 0.43
HRH1 P35367 1/20 0.43
KCNH2 Q12809 1/20 0.43
MDM2 Q00987 1/20 0.42
KMT2A Q03164 2/20 0.42
ATM Q13315 3/20 0.42
CYP3A4 P08684 2/20 0.42
NPC1 O15118 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7440566 1.00 TDP1 (0.47) TDP1L3MBTL1CES1CES2LMNA
SCHEMBL3799471 0.84 CA1 (0.45) CES2LMNAALDH1A1HTTKMT2A
SCHEMBL27781150 0.84 CA1 (0.45) CES2LMNAALDH1A1HTTKMT2A
SCHEMBL12963991 0.82 KMT2A (0.50) TDP1L3MBTL1CES1CES2LMNA
SCHEMBL5137955 0.81 TDP1 (0.48) TDP1L3MBTL1CES1CES2LMNA
SCHEMBL20340201 0.81 TDP1 (0.48) TDP1L3MBTL1CES1CES2LMNA
SCHEMBL11317047 0.80 L3MBTL1 (0.44) TDP1L3MBTL1CES1CES2LMNA
SCHEMBL13971481 0.80 MAPT (0.44) TDP1L3MBTL1CES1CES2LMNA
SCHEMBL15984954 0.79 TDP1 (0.47) TDP1L3MBTL1CES1CES2LMNA
SCHEMBL5555205 0.79 TDP1 (0.47) TDP1L3MBTL1CES1CES2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122028793-A Fungicidal compositions 先正达农作物保护股份公司 2026-05-12 CN claimed
CN-118265452-A Fungicidal compositions 先正达农作物保护股份公司 2024-06-28 CN claimed
US-20230284616-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-09-14 US claimed
US-20230240291-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-08-03 US claimed
US-20230240293-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-08-03 US claimed
US-20230217924-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-07-13 US claimed
US-20230210114-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-07-06 US claimed
US-20230210113-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-07-06 US claimed
CN-115697055-A Fungicidal compositions 先正达农作物保护股份公司 2023-02-03 CN claimed
CN-115697056-A Fungicidal compositions 先正达农作物保护股份公司 2023-02-03 CN claimed
CN-115666241-A Fungicidal compositions 先正达农作物保护股份公司 2023-01-31 CN claimed
CN-115666238-A Fungicidal compositions 先正达农作物保护股份公司 2023-01-31 CN claimed
CN-115666239-A Fungicidal compositions 先正达农作物保护股份公司 2023-01-31 CN claimed
CN-115666240-A Fungicidal compositions 先正达农作物保护股份公司 2023-01-31 CN claimed
CN-122028793-A Fungicidal compositions 先正达农作物保护股份公司 2026-05-12 CN disclosed
CN-118265452-A Fungicidal compositions 先正达农作物保护股份公司 2024-06-28 CN disclosed
US-20230284616-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-09-14 US disclosed
EP-0507484-A1 A pharmaceutical formulation of aureobasidins TAKARA SHUZO CO. LTD. (JP) 1992-10-07 EP disclosed
EP-0500264-A1 Agricultural and horticultural fungicides TAKARA SHUZO CO. LTD. (JP) 1992-08-26 EP disclosed
EP-0443719-A1 Novel R106 compounds TAKARA SHUZO CO. LTD. (JP) 1991-08-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240293-A1 FUNGICIDAL COMPOSITIONS CYP51A1, CYP4X1, CYP1B1 TDP1 601/4885L3MBTL1 1939/4885CES1 224/4885
US-20230284616-A1 FUNGICIDAL COMPOSITIONS CYP51A1, CYP4X1, CYP1B1 TDP1 601/4885L3MBTL1 1939/4885CES1 224/4885
US-20230240291-A1 FUNGICIDAL COMPOSITIONS CYP51A1, DDT, CYP1A2 TDP1 812/4885L3MBTL1 2879/4885CES1 334/4885
US-20230210114-A1 FUNGICIDAL COMPOSITIONS CYP51A1, CYP4X1, CYP1B1 TDP1 601/4885L3MBTL1 1939/4885CES1 224/4885
US-20230217924-A1 FUNGICIDAL COMPOSITIONS CYP51A1, CYP4X1, CYP1B1 TDP1 601/4885L3MBTL1 1939/4885CES1 224/4885
US-20230210113-A1 FUNGICIDAL COMPOSITIONS CYP51A1, CYP4X1, CYP1B1 TDP1 601/4885L3MBTL1 1939/4885CES1 224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.