Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6390168 | 1.00 | TP53 (0.35) | TP53P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL31093177 | 0.81 | TP53 (0.42) | TP53P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL9892480 | 0.81 | TP53 (0.42) | TP53P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL1647708 | 0.78 | P2RX4 (0.31) | TP53P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL11494903 | 0.73 | ALDH1A1 (0.35) | KCNA5 | |
| SCHEMBL7129705 | 0.73 | LMNA (0.35) | — | |
| SCHEMBL22648801 | 0.73 | — | — | |
| SCHEMBL28395101 | 0.73 | — | — | |
| SCHEMBL9750364 | 0.73 | TDP1 (0.36) | TSHR | |
| SCHEMBL10871210 | 0.69 | P2RX4 (0.33) | TP53P2RX1P2RX3P2RX4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578742-A1 | PROCESS FOR PREPARING OPTICALLY PURE ACTIVE COMPOUNDS | ALTANA Pharma AG (DE) | 2005-09-28 | — | — | EP | claimed |
| WO-2004052882-A1 | PROCESS FOR PREPARING OPTICALLY PURE ACTIVE COMPOUNDS | ALTANA PHARMA AG (DE) | 2004-06-24 | — | — | WO | claimed |
| EP-1758889-A1 | PROCESS FOR THE PREPARATION OF PYRIDIN-2-YLMETHYLSULPHINYL-1H-BENZIMIDAZOL COMPOUNDS | Altana Pharma AG (DE) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005118569-A1 | PROCESS FOR THE PREPARATION OF PYRIDIN-2-YLMETHYLSULPHINYL-1H-BENZIMIDAZOL COMPOUNDS | ALTANA PHARMA AG (DE) | 2005-12-15 | — | — | WO | disclosed |