Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367474 | 0.80 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAMEN1KMT2AGAA | |
| SCHEMBL338 | 0.80 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAMEN1KMT2AGAA | |
| SCHEMBL23705539 | 0.80 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAMEN1KMT2AGAA | |
| SCHEMBL29367804 | 0.80 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAMEN1KMT2AGAA | |
| SCHEMBL30563642 | 0.79 | SMN1; SMN2 (0.78) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL4742545 | 0.79 | SMN1; SMN2 (0.78) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL4357939 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNAMEN1KMT2AGAA | |
| Carbimide SCHEMBL10800076 | 0.76 | SMN1; SMN2 (0.90) | SMN1; SMN2LMNAMEN1KMT2AGAA | |
| 1,2-Dichloroethane SCHEMBL28697158 | 0.76 | SMN1; SMN2 (0.90) | SMN1; SMN2LMNAMEN1KMT2AGAA | |
| SCHEMBL11386321 | 0.76 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1519756-B1 | USE OF METAL COMPLEXES CONTAINING PERFLUOROALKYL AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING FOR REPRESENTING INTRAVASCULAR THROMBI | BAYER SCHERING PHARMA AG (DE) | 2007-05-02 | — | — | EP | disclosed |