Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14450929 | 0.89 | PTGDR2 (0.33) | PTGDR2PRCPPLA2G2ACYP1A2CYP2C9 | |
| SCHEMBL5562687 | 0.85 | PTGDR2 (0.33) | PTGDR2 | |
| SCHEMBL5561288 | 0.79 | CYP1A2 (0.40) | PTGDR2CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL5562369 | 0.78 | PTGDR2 (0.32) | PTGDR2 | |
| SCHEMBL5562279 | 0.76 | GABRB3 (0.32) | PTGDR2 | |
| SCHEMBL5560603 | 0.75 | KCNH2 (0.45) | PTGDR2CYP3A4 | |
| SCHEMBL5561074 | 0.75 | PTGDR2 (0.34) | PTGDR2ALDH1A1HPGD | |
| SCHEMBL5561781 | 0.73 | PTGDR2 (0.38) | PTGDR2 | |
| SCHEMBL14472324 | 0.73 | PTGDR2 (0.32) | PTGDR2 | |
| SCHEMBL14454018 | 0.71 | PTGDR2 (0.47) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597235-B1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2007-08-15 | — | — | EP | disclosed |
| US-7241794-B2 | Nonnucleoside reverse transcriptase inhibitors | ROCHEPALO ALTO LLC (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241794-B2 | Nonnucleoside reverse transcriptase inhibitors | ROCHEPALO ALTO LLC (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241794-B2 | Nonnucleoside reverse transcriptase inhibitors | ROCHEPALO ALTO LLC (US) | 2007-07-10 | — | — | US | disclosed |