Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5561074 | 0.90 | PTGDR2 (0.34) | PTGDR2MAPT | |
| SCHEMBL5562687 | 0.82 | PTGDR2 (0.33) | PTGDR2MAPT | |
| SCHEMBL5562369 | 0.80 | PTGDR2 (0.32) | PTGDR2 | |
| SCHEMBL5561781 | 0.80 | PTGDR2 (0.38) | PTGDR2MAPT | |
| SCHEMBL5560926 | 0.79 | KCNH2 (0.47) | PTGDR2MAPT | |
| SCHEMBL5556140 | 0.78 | MAPT (0.38) | PTGDR2MAPT | |
| SCHEMBL5555445 | 0.78 | CYP1A2 (0.41) | PTGDR2 | |
| SCHEMBL14454026 | 0.76 | L3MBTL1 (0.37) | PTGDR2MAPT | |
| SCHEMBL5555794 | 0.76 | PTGDR2 (0.34) | PTGDR2 | |
| SCHEMBL14454018 | 0.75 | PTGDR2 (0.47) | PTGDR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597235-B1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2007-08-15 | — | — | EP | disclosed |
| US-7241794-B2 | Nonnucleoside reverse transcriptase inhibitors | ROCHEPALO ALTO LLC (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241794-B2 | Nonnucleoside reverse transcriptase inhibitors | ROCHEPALO ALTO LLC (US) | 2007-07-10 | — | — | US | disclosed |