Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dinitrophenylene SCHEMBL27294590 | 0.89 | TSHR (0.71) | ALDH1A1LMNATSHRMEN1KMT2A | |
| Nitrobenzene SCHEMBL9669095 | 0.87 | — | — | |
| Nitrobenzene SCHEMBL15525745 | 0.87 | ALDH1A1 (1.00) | ALDH1A1LMNATSHRL3MBTL1MEN1 | |
| Dinitrophenylene SCHEMBL27401564 | 0.87 | TSHR (0.68) | ALDH1A1LMNATSHRMEN1KMT2A | |
| Nitrobenzene SCHEMBL20411 | 0.87 | — | — | |
| Nitrobenzene SCHEMBL1330825 | 0.87 | — | — | |
| Nitrobenzene SCHEMBL2358164 | 0.87 | ALDH1A1 (1.00) | ALDH1A1LMNATSHRL3MBTL1MEN1 | |
| Nitrobenzene SCHEMBL1330714 | 0.87 | — | — | |
| Nitrobenzene SCHEMBL2255264 | 0.87 | ALDH1A1 (1.00) | ALDH1A1LMNATSHRL3MBTL1MEN1 | |
| Nitrobenzene SCHEMBL28272569 | 0.85 | ALDH1A1 (0.84) | ALDH1A1LMNATSHRL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106977523-A | FSHR antagonists with phenyl and nafoxidine structure and preparation method thereof | 河南师范大学 | 2017-07-25 | — | — | CN | disclosed |
| US-7205385-B2 | magnetic resonance imaging agents; poly(amino acid-imaging agent) product can be obtained in high purity without a rigorous purification since all impurities are removed at the monomer synthesis stage | GENERAL ELECTRIC COMPANY (US) | 2007-04-17 | — | — | US | disclosed |
| US-20060104908-A1 | Polymerization method for the synthesis of polypeptide imaging agents | GENERAL ELECTRIC COMPANY (US) | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060104908-A1 | Polymerization method for the synthesis of polypeptide imaging agents | DNPEP, NPPA, NGLY1 | ALDH1A1 4815/4885LMNA 2702/4885HSPB1 3420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.