Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 9/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.69 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.69 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.69 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.69 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.69 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.69 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.69 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.59 |
| ▸ | SELE | P16581 | 4/20 | 0.59 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 2/20 | 0.49 |
| ▸ | F9 | P00740 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17267450 | 0.84 | HDAC3 (0.71) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL699799 | 0.84 | HDAC3 (0.71) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29485573 | 0.84 | HDAC3 (0.71) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL825953 | 0.83 | SLC9A1 (1.00) | SLC9A1 | |
| SCHEMBL13709497 | 0.83 | PLAU (0.66) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6329351 | 0.83 | HDAC3 (0.69) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL9431832 | 0.81 | PLAU (0.67) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| Potassium Ion SCHEMBL14660890 | 0.81 | HDAC3 (0.67) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14660918 | 0.81 | HDAC3 (0.67) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9431027 | 0.81 | PLAU (0.73) | SLC9A1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753428-A2 | KINASE INHIBITORS AS THERAPEUTIC AGENTS | Abbott Laboratories (US) | 2007-02-21 | — | — | EP | disclosed |
| US-20060074102-A1 | Kinase inhibitors as therapeutic agents | ABBOTT LABORATORIES | 2006-04-06 | — | — | US | disclosed |
| WO-2005110410-A2 | KINASE INHIBITORS AS THERAPEUTIC AGENTS | ABBOTT LABORATORIES (US) | 2005-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074102-A1 | Kinase inhibitors as therapeutic agents | ABL1, MAP3K19, MAP3K20 | SLC9A1 3495/4885HDAC3 1316/4885HDAC4 1537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.