Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.73 |
| ▸ | F9 | P00740 | 1/20 | 0.73 |
| ▸ | F10 | P00742 | 1/20 | 0.73 |
| ▸ | SLC9A1 | P19634 | 8/20 | 0.62 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.54 |
| ▸ | SELE | P16581 | 3/20 | 0.54 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.47 |
| ▸ | PLK4 | O00444 | 2/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 2/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.47 |
| ▸ | CDK1 | P06493 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | PRKACA | P17612 | 2/20 | 0.47 |
| ▸ | FLT1 | P17948 | 2/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440564 | 0.86 | PLAU (0.63) | PLAUF9F10SLC9A1ICAM1 | |
| SCHEMBL4312886 | 0.84 | F9 (1.00) | PLAUF9F10SLC9A1 | |
| SCHEMBL4853915 | 0.84 | PLAU (0.61) | PLAUF9F10SLC9A1ICAM1 | |
| Hydrochloric Acid SCHEMBL9431849 | 0.83 | PLAU (1.00) | PLAUF9F10SLC9A1 | |
| SCHEMBL31117854 | 0.81 | SLC9A1 (0.70) | PLAUF9F10SLC9A1ICAM1 | |
| SCHEMBL5555882 | 0.81 | SLC9A1 (0.70) | PLAUF9F10SLC9A1ICAM1 | |
| SCHEMBL829725 | 0.80 | SLC9A1 (0.56) | PLAUF9F10SLC9A1ICAM1 | |
| SCHEMBL31117871 | 0.78 | SLC9A1 (0.56) | PLAUF9F10SLC9A1ICAM1 | |
| SCHEMBL12330453 | 0.78 | PLAU (0.54) | PLAUF9F10SLC9A1DYRK1A | |
| SCHEMBL22364128 | 0.77 | SLC9A1 (0.72) | PLAUF9F10SLC9A1ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046789-B1 | LABELLED ANALOGUES OF HALOBENZAMIDES AS RADIOPHARMACEUTICALS | INST NAT SANTE RECH MED (FR) | 2012-09-05 | — | — | EP | disclosed |
| EP-2363399-A1 | Labelled analogues of halobenzamides as radiopharmaceuticals | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-09-07 | — | — | EP | disclosed |
| WO-2008012782-A2 | LABELLED ANALOGUES OF HALOBENZAMIDES AS RADIOPHARMACEUTICALS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2008-01-31 | — | — | WO | disclosed |
| US-5340833-A | Antiarthritic, antiinflammatory, antitumor agents | EISAI CO., LTD. (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0568289-A2 | Benzothiophenes and thienothiophenes and related compounds useful, for example, as urokinase inhibitors | Eisai Co., Ltd. (JP) | 1993-11-03 | — | — | EP | disclosed |