Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3365421 | 0.79 | KMT2A (0.41) | LMNAP2RX7SLC6A2SLC6A4ADRB2 | |
| SCHEMBL10876266 | 0.78 | LMNA (0.69) | LMNAHIF1AGALR3ADRB2ADRB1 | |
| SCHEMBL12231496 | 0.77 | GRIN1 (0.57) | LMNAHIF1AGALR3GRIN1GRIN2A | |
| SCHEMBL14830681 | 0.76 | ACP3 (0.46) | LMNAP2RX7SLC6A2SLC6A4ADRB2 | |
| SCHEMBL16552514 | 0.75 | LMNA (0.49) | LMNAHIF1AGALR3SLC6A2SLC6A4 | |
| SCHEMBL16552522 | 0.75 | SLC6A2 (0.48) | LMNAHIF1AGALR3SLC6A2SLC6A4 | |
| SCHEMBL17071892 | 0.74 | ACP3 (0.47) | LMNASLC6A2SLC6A4ADRB2ADRB1 | |
| SCHEMBL16771227 | 0.74 | ACP3 (0.46) | LMNASLC6A2SLC6A4ADRB2ADRB1 | |
| Benzene SCHEMBL27711286 | 0.73 | KDM4E (0.55) | LMNAHIF1AGALR3SLC6A2SLC6A4 | |
| Benzene SCHEMBL27731714 | 0.73 | KDM4E (0.55) | LMNAHIF1AGALR3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807388-A2 | ACYCLIC HYDRAZIDES AS CANNABINOID RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006041797-A2 | ACYCLIC HYDRAZIDES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2006-04-20 | — | — | WO | disclosed |