Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 5/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243485 | 0.90 | MMP9 (0.53) | NPC1RAB9AKMT2AMMP9MMP1 | |
| SCHEMBL5553492 | 0.87 | MMP9 (0.46) | KMT2AMMP9MMP1 | |
| SCHEMBL5559022 | 0.83 | MMP9 (0.52) | KMT2AMMP9MMP1 | |
| SCHEMBL5558922 | 0.82 | MMP9 (0.51) | KMT2AMMP9MMP1 | |
| SCHEMBL5559915 | 0.82 | MMP9 (0.49) | KMT2AMMP9MMP1 | |
| SCHEMBL5553677 | 0.79 | MMP9 (0.45) | KMT2AMMP9MMP1 | |
| SCHEMBL5553436 | 0.79 | OPRL1 (0.51) | KMT2AMMP9MMP1 | |
| SCHEMBL5553528 | 0.78 | CA1 (0.52) | NPC1RAB9AKMT2AMMP9MMP1 | |
| SCHEMBL5558128 | 0.78 | CYP3A4 (0.52) | KMT2AMMP9MMP1 | |
| SCHEMBL5558248 | 0.78 | PRKCI (0.54) | KMT2AMMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509516-B1 | INHIBITORS OF THE GPIB -VWF INTERACTION, THEIR PREPARATION AND USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-01-31 | — | — | EP | claimed |