Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | GNG2 | P59768 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3238192 | 0.90 | CA1 (0.60) | CA1CA2STAT3NPC1RAB9A | |
| SCHEMBL5553436 | 0.81 | OPRL1 (0.51) | OPRL1KMT2AMMP9APAF1USP2 | |
| SCHEMBL5559915 | 0.81 | MMP9 (0.49) | KMT2AMMP9MEN1MMP1ALOX15 | |
| SCHEMBL5559022 | 0.81 | MMP9 (0.52) | OPRL1KMT2AMMP9MEN1MMP1 | |
| SCHEMBL5558922 | 0.79 | MMP9 (0.51) | OPRL1KMT2AMMP9MEN1MMP1 | |
| SCHEMBL5553492 | 0.79 | MMP9 (0.46) | KMT2AMMP9MEN1MMP1ALOX15 | |
| SCHEMBL5558063 | 0.78 | NPC1 (0.52) | NPC1RAB9AKMT2AMMP9MMP1 | |
| SCHEMBL5558128 | 0.78 | CYP3A4 (0.52) | KMT2AMMP9MMP1 | |
| SCHEMBL5558153 | 0.77 | OPRL1 (0.54) | NPC1RAB9AOPRL1MMP9MAPT | |
| SCHEMBL5558427 | 0.77 | MMP9 (0.49) | NPC1RAB9AOPRL1KMT2AMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509516-B1 | INHIBITORS OF THE GPIB -VWF INTERACTION, THEIR PREPARATION AND USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-01-31 | — | — | EP | claimed |