⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29483911 | 1.00 | — | — | |
| SCHEMBL23498787 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL30340427 | 0.97 | — | — | |
| SCHEMBL1604317 | 0.80 | — | — | |
| SCHEMBL22613944 | 0.80 | — | — | |
| SCHEMBL584025 | 0.80 | — | — | |
| SCHEMBL820453 | 0.80 | — | — | |
| SCHEMBL21098299 | 0.80 | CYP2C9 (0.33) | — | |
| SCHEMBL2836928 | 0.80 | — | — | |
| SCHEMBL14441066 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100221809-A1 | Compositions and Methods for the Isolation of Biologically Active Proteins | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2010-09-02 | — | — | US | disclosed |
| US-20100221809-A1 | Compositions and Methods for the Isolation of Biologically Active Proteins | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2010-09-02 | — | — | US | disclosed |
| WO-2007130353-A2 | PHASE 2 INDUCERS, PPAR-ALPHA AGONISTS AND RELATED SIGNALLING PATHWAYS PROTECT CARTILAGE AGAINST INFLAMMATION, APOPTOSIS AND STRESS | JOHNS HOPKINS UNIVERSITY (US) | 2007-11-15 | — | — | WO | disclosed |
| US-20070197538-A1 | Anti-vascular and anti-proliferation methods, therapies, and combinations employing specific tyrosine kinase inhibitors | AVENTIS PHARMA S.A. (FR) | 2007-08-23 | — | — | US | disclosed |