Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 9/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 9/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5552970 | 0.96 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1TSHRMEN1HTT | |
| SCHEMBL5551871 | 0.89 | MAPT (0.40) | SMN1; SMN2ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10266176 | 0.88 | PIK3CD (0.43) | KMT2APIK3CDPIK3CBCYP3A4PIK3CA | |
| SCHEMBL5556178 | 0.87 | L3MBTL1 (0.39) | SMN1; SMN2ALDH1A1TSHRMEN1HTT | |
| SCHEMBL5556851 | 0.83 | DTYMK (0.38) | SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL10265374 | 0.81 | KDM1A (0.38) | ALDH1A1PIK3CDPIK3CBCYP3A4L3MBTL1 | |
| SCHEMBL5527791 | 0.80 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1TSHRMEN1HTT | |
| SCHEMBL9642917 | 0.77 | RAB9A (0.40) | SMN1; SMN2ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL5528693 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1TSHRMEN1HTT | |
| SCHEMBL5553132 | 0.76 | KMT2A (0.48) | SMN1; SMN2ALDH1A1TSHRMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | SMN1; SMN2 4646/4885ALDH1A1 2042/4885TSHR 3395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.