SCHEMBL555855

SCHEMBL555855

NCCCC[C@H](N)C(=O)N1C(=O)C=CC1=O

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 15/20 0.51
DPP8 Q6V1X1 8/20 0.51
DPP9 Q86TI2 7/20 0.51
GSR P00390 1/20 0.48
DPP4 P27487 7/20 0.45
FAP Q12884 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL555853 1.00 DPP7 (0.51) DPP7DPP8DPP9GSRDPP4
SCHEMBL28141312 0.76 GSR (0.44) DPP7DPP8DPP9GSRDPP4
SCHEMBL29533820 0.75 DPP7 (0.51) DPP7DPP8DPP9GSRDPP4
Lysine SCHEMBL28980842 0.71 GSR (0.74) DPP7DPP8DPP9GSR
Lysine SCHEMBL28980840 0.71 GSR (0.74) DPP7DPP8DPP9GSR
Lysine SCHEMBL1221228 0.69 GSR (0.95) GSR
Lysine SCHEMBL1220993 0.69 GSR (0.95) GSR
Lysine SCHEMBL318676 0.69 GSR (0.95) GSR
Lysine SCHEMBL30915820 0.69 GSR (0.95) GSR
SCHEMBL18499975 0.69 GSR (0.64) DPP7DPP8DPP9GSRDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2398498-B1 ANTIBODY MOLECULES HAVING SPECIFICITY FOR HUMAN OX40 UCB BIOPHARMA SPRL (BE) 2018-09-05 EP claimed
EP-3339325-A1 BACTERIAL HOST STRAIN EXPRESSING RECOMBINANT DSBC UCB Biopharma SPRL (BE) 2018-06-27 EP claimed
US-9957328-B2 Bacterial host strain expressing recombinant DSBC UCB PHARMA, S.A. (GB) 2018-05-01 US claimed
US-20170335003-A1 BACTERIAL HOST STRAIN EXPRESSING RECOMBINANT DSBC CELLTECH R&D LTD. (GB) 2017-11-23 US claimed
EP-2731973-B1 BACTERIAL HOST STRAIN EXPRESSING RECOMBINANT DSBC UCB BIOPHARMA SPRL (BE) 2017-11-15 EP claimed
US-9725516-B2 Bacterial host strain expressing recombinant DSBC UCB PHARMA, S.A. (BE) 2017-08-08 US claimed
US-20140141468-A1 BACTERIAL HOST STRAIN EXPRESSING RECOMBINANT DSBC UCB PHARMA, S.A. (BE) 2014-05-22 US claimed
EP-2731973-A1 BACTERIAL HOST STRAIN EXPRESSING RECOMBINANT DSBC UCB Pharma, S.A. (BE) 2014-05-21 EP claimed
US-8614295-B2 Antibody molecules having specificity for human OX40 UCB PHARMA S.A. (BE) 2013-12-24 US claimed
US-20130330344-A1 ANTIBODY MOLECULES HAVING SPECIFICITY FOR HUMAN OX40 UCB PHARMA S.A. (BE) 2013-12-12 US claimed
US-20050181448-A1 Biological products UCB S.A. (BE) 2005-08-18 US claimed
CN-1568331-A Biological products CELLTECH R&D LTD (GB) 2005-01-19 CN claimed
WO-2004072116-A2 ANTIBODY MOLECULES HAVING SPECIFICITY FOR HUMAN IL-1β CELLTECH R & D LIMITED (GB) 2004-08-26 WO claimed
EP-1438340-A2 ANTIBODIES AGAINST KDR, THEIR PRODUCTION AND USES Celltech R & D Limited (GB) 2004-07-21 EP claimed
US-20030157061-A1 Combinations of a cyclooxygenase-2 selective inhibitor and a TNFalpha antagonist and therapeutic uses therefor PHARMACIA CORPORATION (US) 2003-08-21 US claimed
WO-2003031475-A2 ANTIBODIES AGAINST KDR, THEIR PRODUCTION AND USES CELLTECH R & D LIMITED (GB) 2003-04-17 WO claimed
EP-1287140-A1 ANTIBODY MOLECULES HAVING SPECIFICITY FOR HUMAN TUMOR NECROSIS FACTOR ALPHA, AND USE THEREOF Celltech R&D Limited (GB) 2003-03-05 EP claimed
US-20030026805-A1 Biological products UCB S.A. (BE) 2003-02-06 US claimed
US-20020151682-A1 Biological products UCB S.A. (BE) 2002-10-17 US claimed
WO-2001094585-A1 ANTIBODY MOLECULES HAVING SPECIFICITY FOR HUMAN TUMOR NECROSIS FACTOR ALPHA, AND USE THEREOF CELLTECH R & D LIMITED (GB) 2001-12-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130330344-A1 ANTIBODY MOLECULES HAVING SPECIFICITY FOR HUMAN OX40 LY96, IGSF11, FCGR1A DPP7 4445/4885DPP8 4375/4885DPP9 4018/4885
US-20030157061-A1 Combinations of a cyclooxygenase-2 selective inhibitor and a TNFalpha antagonist and therapeutic uses therefor TNF, TNFRSF1A, CD40 DPP7 1077/4885DPP8 1089/4885DPP9 2844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.