Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.74 |
| ▸ | ARG2 | P78540 | 4/20 | 0.47 |
| ▸ | ARG1 | P05089 | 3/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL28980840 | 1.00 | GSR (0.74) | GSRARG2ARG1CPB2RNPEP | |
| Lysine SCHEMBL28214073 | 0.86 | GSR (0.91) | GSRARG2ARG1CPB2RNPEP | |
| Lysine SCHEMBL456381 | 0.86 | GSR (1.00) | GSRARG2ARG1CPB2RNPEP | |
| Lysine SCHEMBL1000151 | 0.86 | GSR (1.00) | GSRARG2ARG1CPB2RNPEP | |
| Lysine SCHEMBL2802757 | 0.86 | GSR (1.00) | GSRARG2ARG1CPB2RNPEP | |
| Lysine SCHEMBL3359527 | 0.86 | GSR (1.00) | GSRARG2ARG1CPB2RNPEP | |
| Lysine SCHEMBL12867528 | 0.86 | GSR (1.00) | GSRARG2ARG1CPB2RNPEP | |
| Lysine SCHEMBL9439278 | 0.86 | GSR (1.00) | GSRARG2ARG1CPB2RNPEP | |
| Lysine SCHEMBL7343 | 0.86 | GSR (1.00) | GSRARG2ARG1CPB2RNPEP | |
| Lysine SCHEMBL1645 | 0.86 | GSR (1.00) | GSRARG2ARG1CPB2RNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115939474-A | Microbial photoelectrochemical system and construction method and application thereof | 福建农林大学 | 2023-04-07 | — | — | CN | claimed |