Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5559588 | 0.82 | PTGS1 (0.36) | PTGS2PTGS1 | |
| SCHEMBL5554179 | 0.80 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL5553729 | 0.79 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL5560456 | 0.78 | PTGS2 (0.41) | PTGS2PTGS1 | |
| SCHEMBL5559111 | 0.78 | PPARG (0.40) | PTGS2PTGS1 | |
| SCHEMBL5554036 | 0.77 | PTGS2 (0.42) | PTGS2PTGS1 | |
| SCHEMBL5554594 | 0.75 | SRC (0.36) | PTGS2 | |
| SCHEMBL5559081 | 0.73 | PTGS1 (0.43) | PTGS2PTGS1 | |
| SCHEMBL5553652 | 0.73 | PTGS2 (0.37) | PTGS2PTGS1 | |
| SCHEMBL5560793 | 0.72 | HDAC3 (0.36) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1643961-A4 | COX-2 AND FAAH INHIBITORS | MICROBIA INC (US) | 2007-09-12 | — | — | EP | disclosed |
| EP-1643961-A2 | COX-2 AND FAAH INHIBITORS | Microbia, Inc. (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005002525-A2 | COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2005-01-13 | — | — | WO | disclosed |