⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11392903 | 0.79 | — | — | |
| SCHEMBL5374083 | 0.79 | LMNA (0.42) | — | |
| SCHEMBL1504371 | 0.75 | — | — | |
| SCHEMBL1504373 | 0.75 | — | — | |
| SCHEMBL19640970 | 0.75 | — | — | |
| SCHEMBL4668090 | 0.75 | — | — | |
| SCHEMBL3486713 | 0.75 | LMNA (0.48) | — | |
| SCHEMBL23143671 | 0.72 | — | — | |
| SCHEMBL28472492 | 0.72 | — | — | |
| SCHEMBL88030 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290531-B2 | Synthetic LTA mimetics and use thereof as vaccine component for therapy and/or prophylaxis against gram-positive infections | Universitätsklinikum Freiburg (DE) | 2016-03-22 | — | — | US | disclosed |
| EP-2500349-B1 | Synthetic LTA mimetics and use thereof as vaccine component for therapy and/or prophylaxis against gram-positive infections | Universitätsklinikum Freiburg (DE) | 2015-05-06 | — | — | EP | disclosed |
| US-20140050741-A1 | SYNTHETIC LTA MIMETICS AND USE THEREOF AS VACCINE COMPONENT FOR THERAPY AND/OR PROPHYLAXIS AGAINST GRAM-POSITIVE INFECTIONS | UNIVERSITEIT LEIDEN (NL) | 2014-02-20 | — | — | US | disclosed |
| EP-2500349-A1 | Synthetic LTA mimetics and use thereof as vaccine component for therapy and/or prophylaxis against gram-positive infections | Universitätsklinikum Freiburg (DE) | 2012-09-19 | — | — | EP | disclosed |
| WO-2012119846-A1 | SYNTHETIC LTA MIMETICS AND USE THEREOF AS VACCINE COMPONENT FOR THERAPY AND/OR PRO-PHYLAXIS AGAINST GRAM-POSITIVE INFECTIONS | Universitätsklinikum Freiburg (DE) | 2012-09-13 | — | — | WO | disclosed |
| EP-1601789-A4 | MODULATION OF IMMUNOSTIMULATORY PROPERTIES OF OLIGONUCLEOTIDE-BASED COMPOUNDS BY UTILIZING MODIFIED IMMUNOSTIMULATORY DINUCLEOTIDES | IDERA PHARMACEUTICALS INC (US) | 2007-10-31 | — | — | EP | disclosed |
| EP-1601789-A2 | MODULATION OF IMMUNOSTIMULATORY PROPERTIES OF OLIGONUCLEOTIDE-BASED COMPOUNDS BY UTILIZING MODIFIED IMMUNOSTIMULATORY DINUCLEOTIDES | HYBRIDON, INC. (US) | 2005-12-07 | — | — | EP | disclosed |
| WO-2004064782-A2 | MODULATION OF IMMUNOSTIMULATORY PROPERTIES OF OLIGONUCLEOTIDE-BASED COMPOUNDS BY UTILIZING MODIFIED IMMUNOSTIMULATORY DINUCLEOTIDES | HYBRIDON, INC. (US) | 2004-08-05 | — | — | WO | disclosed |
| US-5624802-A | OLIGONUCLEIC ACIDS SUCH AS DNA OR RNA WITH SINGLE OR DOUBLE STRANDS HAVING COMB OR FORK STRUCTURES | CHIRON CORPORATION (US) | 1997-04-29 | — | — | US | disclosed |
| US-5614362-A | Nucleic acid hybridization assay for hepatitis B virus DNA | CHIRON CORPORATION (US) | 1997-03-25 | — | — | US | disclosed |
| US-5571670-A | Nucleic acid probes useful in detecting Chlamydia trachomatis and amplified nucleic acid hybridization assays using same | CHIRON CORPORATION (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0469066-B1 | IMPROVED NUCLEIC ACID HYBRIDIZATION ASSAYS FOR HBV EMPLOYING AMPLIFICATION | CHIRON CORP (US) | 1996-05-29 | — | — | EP | disclosed |
| EP-0317077-B1 | Nucleic acid multimers and amplified nucleic acid hybridization assays using same | CHIRON CORP (US) | 1996-01-31 | — | — | EP | disclosed |
| US-5359100-A | Immunoassay | CHIRON CORPORATION (US) | 1994-10-25 | — | — | US | disclosed |
| EP-0469066-A4 | IMPROVED AMPLIFIED NUCLEIC ACID HYBRIDIZATION ASSAYS FOR HBV | — | 1992-07-08 | — | — | EP | disclosed |
| US-5124246-A | Improved hybridization assays for hepatitis B virus, Neissera gonorrhoeae, penicillin and tetracycline resistance in N. gonorrhoeae and Chlamydia trachomatis | CHIRON CORPORATION (US) | 1992-06-23 | — | — | US | disclosed |
| EP-0469066-A1 | IMPROVED AMPLIFIED NUCLEIC ACID HYBRIDIZATION ASSAYS FOR HBV. | CHIRON CORP (US) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990013667-A1 | IMPROVED AMPLIFIED NUCLEIC ACID HYBRIDIZATION ASSAYS FOR HBV | CHIRON CORPORATION (US) | 1990-11-15 | — | — | WO | disclosed |
| EP-0317077-A1 | Nucleic acid multimers and amplified nucleic acid hybridization assays using same | CHIRON CORPORATION (US) | 1989-05-14 | — | — | EP | disclosed |
| WO-1989003891-A1 | NUCLEIC ACID MULTIMERS AND AMPLIFIED NUCLEIC ACID HYBRIDIZATION ASSAYS USING SAME | CHIRON CORPORATION (US) | 1989-05-05 | — | — | WO | disclosed |