SCHEMBL3486713

SCHEMBL3486713

NP(O)OC[C@@H](O)[C@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TDP1 Q9NUW8 1/20 0.46
USP2 O75604 1/20 0.38
SLCO1B1 Q9Y6L6 1/20 0.38
KDM4E B2RXH2 2/20 0.35
PDE4A P27815 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4295909 0.76 MPI (0.35)
SCHEMBL16703164 0.76 MPI (0.35)
SCHEMBL5558849 0.75
Sorbitol SCHEMBL29846994 0.72 LMNA (0.79) LMNAL3MBTL1TDP1USP2SLCO1B1
Mannitol SCHEMBL27564656 0.72 LMNA (0.79) LMNAL3MBTL1TDP1USP2SLCO1B1
Mannitol SCHEMBL4971188 0.72 LMNA (0.58) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL1129672 0.72 LMNA (0.58) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL5032170 0.72 LMNA (0.58) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL1671960 0.72 LMNA (0.58) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL619757 0.71 LMNA (0.65) LMNAL3MBTL1TDP1USP2SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100009865-A1 OLIGONUCLEOTIDE ARRAYS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2010-01-14 US disclosed
EP-2097433-A2 OLIGONUCLEOTIDE ARRAYS Katholieke Universiteit Leuven (BE) 2009-09-09 EP disclosed
WO-2008037036-A2 OLIGONUCLEOTIDE ARRAYS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2008-04-03 WO disclosed