Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | PTPRF | P10586 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPRA | P18433 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2338559 | 0.84 | MAPT (0.66) | MAPTALDH1A1TSHRTDP1KMT2A | |
| SCHEMBL2339204 | 0.84 | MAPT (0.60) | MAPTALDH1A1TSHRTDP1KMT2A | |
| SCHEMBL2623090 | 0.84 | TDP1 (0.46) | MAPTALDH1A1TSHRTDP1KMT2A | |
| SCHEMBL2623089 | 0.84 | TSHR (0.52) | MAPTALDH1A1TSHRTDP1KMT2A | |
| SCHEMBL11640056 | 0.81 | MAPT (0.46) | MAPTALDH1A1HRH4TSHRTDP1 | |
| SCHEMBL19129811 | 0.81 | TSHR (0.50) | MAPTALDH1A1HRH4TSHRKMT2A | |
| SCHEMBL571574 | 0.79 | MAPT (0.51) | MAPTALDH1A1TSHRTDP1KMT2A | |
| SCHEMBL27361146 | 0.77 | TDP1 (0.41) | MAPTALDH1A1TSHRTDP1KMT2A | |
| SCHEMBL4244587 | 0.77 | MAPT (0.53) | MAPTALDH1A1TSHRTDP1KMT2A | |
| SCHEMBL125904 | 0.77 | CASP1 (0.52) | ALDH1A1HRH4TSHRTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018148224-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) | 2018-08-16 | — | — | WO | claimed |
| CN-112955011-B | Compositions comprising pyridine carboxylic acid herbicides with photosystem II and optionally HPPD inhibitor herbicides | 科迪华农业科技有限责任公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-112955011-A | Compositions comprising a carboxypyridine herbicide in combination with a photosystem II and optionally an HPPD inhibitor herbicide | 科迪华农业科技有限责任公司 | 2021-06-11 | — | — | CN | disclosed |
| WO-2018148224-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) | 2018-08-16 | — | — | WO | disclosed |
| US-20070207928-A1 | Oil-in-water suspoemulsions comprising hydroxybenzonitriles which are active in plants | BAYER CROPSCIENCE GMBH (DE) | 2007-09-06 | — | — | US | disclosed |