Sugi Predict

Sugi Predict / Compounds / Ciaftalan

Ciaftalan

Ciaftalan

SCHEMBL5559402

CCCCCCCCCCCCCCCCCCS(N)(=O)=O.c1ccc2c(c1)-c1nc-2nc2[nH]c(nc3nc(nc4[nH]c(n1)c1ccccc41)-c1ccccc1-3)c1ccccc21

nearest known ligand 0.39

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.39
▸ THRB P10828 1/20 0.39
▸ APEX1 P27695 1/20 0.39
▸ RECQL P46063 1/20 0.39
▸ BLM P54132 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ PARP14 Q460N5 1/20 0.37
▸ CA2 P00918 1/20 0.36
▸ ELANE P08246 2/20 0.35
▸ ALOX5AP P20292 2/20 0.34
▸ FEN1 P39748 2/20 0.34
▸ CES1 P23141 2/20 0.34
▸ CDC25A P30304 1/20 0.34
▸ TLR8 Q9NR97 1/20 0.34
▸ KCNA3 P22001 1/20 0.33
▸ FAAH O00519 1/20 0.33
▸ MGLL Q99685 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ciaftalan SCHEMBL5564158 1.00 MEN1 (0.39) MEN1THRBAPEX1RECQLBLM
Ciaftalan SCHEMBL5563423 1.00 MEN1 (0.39) MEN1THRBAPEX1RECQLBLM
Ciaftalan SCHEMBL5563419 0.85 RELA (0.43) MEN1THRBAPEX1RECQLBLM
Ciaftalan SCHEMBL11520284 0.85 MEN1 (0.39) MEN1THRBAPEX1RECQLBLM
Ciaftalan SCHEMBL28514833 0.82 TLR8 (0.44) MEN1KMT2AELANETLR8
Ciaftalan SCHEMBL29211555 0.82 TLR8 (0.44) MEN1KMT2AELANETLR8
SCHEMBL11694369 0.82 PARP14 (0.42) MEN1KMT2APARP14ALOX5APFEN1
SCHEMBL5796989 0.82 PARP14 (0.42) MEN1KMT2APARP14ALOX5APFEN1
SCHEMBL15283270 0.81 PARP14 (0.41) MEN1KMT2APARP14ALOX5APFEN1
SCHEMBL5564159 0.81 PARP14 (0.53) PARP14ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7211609-B2 Warp-free pigment compositions comprising phthalocyanine pigments CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-05-01 — — US disclosed
EP-1513899-B1 WARP-FREE PIGMENT COMPOSITIONS COMPRISING PHTHALOCYANINE PIGMENTS CIBA SC HOLDING AG (CH) 2006-11-29 — — EP disclosed
US-20050197432-A1 Warp-free pigment compositions comprising phthalocyanine pigments CIBA SPECIALTY CHEMICALS CORP. 2005-09-08 — — US disclosed
EP-1513899-A1 WARP-FREE PIGMENT COMPOSITIONS COMPRISING PHTHALOCYANINE PIGMENTS Ciba SC Holding AG (CH) 2005-03-16 — — EP disclosed
WO-2004000949-A1 WARP-FREE PIGMENT COMPOSITIONS COMPRISING PHTHALOCYANINE PIGMENTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-12-31 — — WO disclosed