SCHEMBL5564159

SCHEMBL5564159

CCCCCCCCCCCCS(=O)(=O)Nc1cccc2c3nc4nc(nc5[nH]c(nc6nc(nc([nH]3)c12)-c1ccccc1-6)c1ccccc51)-c1ccccc1-4

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PARP14 Q460N5 4/20 0.53
BRD4 O60885 1/20 0.43
ALOX5AP P20292 1/20 0.42
FEN1 P39748 1/20 0.42
BRAF P15056 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1719615 1.00 PARP14 (0.53) PARP14BRD4ALOX5APFEN1BRAF
SCHEMBL5796989 0.88 PARP14 (0.42) PARP14BRD4ALOX5APFEN1BRAF
SCHEMBL11694369 0.88 PARP14 (0.42) PARP14BRD4ALOX5APFEN1BRAF
SCHEMBL15283270 0.87 PARP14 (0.41) PARP14BRD4ALOX5APFEN1BRAF
SCHEMBL27919956 0.84 PARP14 (0.39) PARP14BRD4ALOX5APFEN1BRAF
Ciaftalan SCHEMBL5563419 0.83 RELA (0.43) PARP14BRD4
SCHEMBL9182220 0.82 UTS2R (0.46) PARP14
SCHEMBL9181704 0.82 UTS2R (0.46) PARP14
SCHEMBL28627581 0.81 PARP14 (0.36) PARP14BRD4
Ciaftalan SCHEMBL5559402 0.81 MEN1 (0.39) PARP14ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7211609-B2 Warp-free pigment compositions comprising phthalocyanine pigments CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-05-01 US disclosed
EP-1513899-B1 WARP-FREE PIGMENT COMPOSITIONS COMPRISING PHTHALOCYANINE PIGMENTS CIBA SC HOLDING AG (CH) 2006-11-29 EP disclosed
US-20050197432-A1 Warp-free pigment compositions comprising phthalocyanine pigments CIBA SPECIALTY CHEMICALS CORP. 2005-09-08 US disclosed
CN-1662611-A Warp-free pigment compositions comprising phthalocyanine pigments CIBA SC HOLDING AG (CH) 2005-08-31 CN disclosed
EP-1513899-A1 WARP-FREE PIGMENT COMPOSITIONS COMPRISING PHTHALOCYANINE PIGMENTS Ciba SC Holding AG (CH) 2005-03-16 EP disclosed
WO-2004000949-A1 WARP-FREE PIGMENT COMPOSITIONS COMPRISING PHTHALOCYANINE PIGMENTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-12-31 WO disclosed