Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK7 | Q13164 | 10/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5558909 | 0.98 | MAPK7 (0.39) | MAPK7SCN9AHSD11B1MGLLPPARG | |
| SCHEMBL5560242 | 0.86 | PPARG (0.37) | PPARG | |
| SCHEMBL5553908 | 0.81 | PPARG (0.36) | PPARG | |
| SCHEMBL5559277 | 0.80 | SCN9A (0.37) | MAPK7SCN9AHSD11B1MGLLPPARG | |
| SCHEMBL5554445 | 0.80 | PPARG (0.37) | HSD11B1PPARG | |
| SCHEMBL5560793 | 0.80 | HDAC3 (0.36) | PPARG | |
| SCHEMBL5553749 | 0.79 | MAPK7 (0.41) | MAPK7PPARGHCRTR2PDE4BPDE4D | |
| SCHEMBL5553805 | 0.78 | HRH3 (0.35) | HSD11B1MGLLPPARGHCRTR2 | |
| SCHEMBL5559111 | 0.77 | PPARG (0.40) | PPARGPTGDR2 | |
| SCHEMBL5800878 | 0.77 | PPARG (0.35) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1643961-A4 | COX-2 AND FAAH INHIBITORS | MICROBIA INC (US) | 2007-09-12 | — | — | EP | disclosed |
| EP-1643961-A2 | COX-2 AND FAAH INHIBITORS | Microbia, Inc. (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005002525-A2 | COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2005-01-13 | — | — | WO | disclosed |