Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29424100 | 0.76 | TSHR (0.41) | TSHRALDH1A1HPGDZDHHC20ZDHHC2 | |
| SCHEMBL12775037 | 0.73 | TSHR (0.38) | TSHRALDH1A1HPGD | |
| SCHEMBL27828975 | 0.73 | GAA (0.43) | TSHRALDH1A1 | |
| SCHEMBL12775025 | 0.73 | TSHR (0.61) | TSHRALDH1A1HPGD | |
| SCHEMBL373448 | 0.72 | — | — | |
| SCHEMBL27595366 | 0.71 | TSHR (0.44) | TSHRALDH1A1HPGDZDHHC20ZDHHC2 | |
| SCHEMBL12775026 | 0.70 | TSHR (0.57) | TSHRALDH1A1HPGD | |
| SCHEMBL15745731 | 0.70 | TSHR (0.31) | TSHR | |
| SCHEMBL12775040 | 0.69 | — | — | |
| SCHEMBL14843014 | 0.68 | TSHR (0.41) | TSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137690-B2 | PEG-BASED MACROMONOMERS, CHEMICALLY INERT POLYMERS PREPARED THEREFROM AND THE USE OF THESE POLYMERS FOR ORGANIC SYNTHESIS AND ENZYME REACTIONS | CARLSBERG AS (DK) | 2007-01-24 | — | — | EP | claimed |
| US-7064179-B1 | Peg-based macromonomers, chemically inert polymers prepared therefrom and the use of these polymers for organic synthesis and enzyme reactions | CARLSBERG A/S (DK) | 2006-06-20 | — | — | US | claimed |
| EP-1137690-B1 | PEG-BASED MACROMONOMERS, CHEMICALLY INERT POLYMERS PREPARED THEREFROM AND THE USE OF THESE POLYMERS FOR ORGANIC SYNTHESIS AND ENZYME REACTIONS | CARLSBERG AS (DK) | 2004-11-10 | — | — | EP | claimed |
| EP-1137690-A2 | PEG-BASED MACROMONOMERS, CHEMICALLY INERT POLYMERS PREPARED THEREFROM AND THE USE OF THESE POLYMERS FOR ORGANIC SYNTHESIS AND ENZYME REACTIONS | Carlsberg A/S (DK) | 2001-10-04 | — | — | EP | claimed |
| WO-2000018823-A2 | PEG-BASED MACROMONOMERS, CHEMICALLY INERT POLYMERS PREPARED THEREFROM AND THE USE OF THESE POLYMERS FOR ORGANIC SYNTHESIS AND ENZYME REACTIONS | CARLSBERG A/S (DK) | 2000-04-06 | — | — | WO | claimed |