SCHEMBL14843014

SCHEMBL14843014

C=CC(=O)C[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.41
ALDH1A1 P00352 5/20 0.41
HPGD P15428 1/20 0.32
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
CYP3A4 P08684 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28569489 0.80 ALDH1A1 (0.42) TSHRALDH1A1
SCHEMBL7952686 0.74
SCHEMBL12775043 0.71 ALDH1A1 (0.31) TSHRALDH1A1
SCHEMBL397010 0.71 TSHR (0.47) TSHRALDH1A1HPGDTP53HIF1A
SCHEMBL397193 0.69 TSHR (0.50) TSHRALDH1A1HPGDTP53HIF1A
SCHEMBL16620348 0.69 ALDH1A1 (0.37) TSHRALDH1A1
Acrylic Acid SCHEMBL28364193 0.69 LMNA (0.56) TSHRALDH1A1HPGDTP53HIF1A
SCHEMBL4757613 0.68 TSHR (0.44) TSHRALDH1A1HPGD
SCHEMBL5559849 0.68 TSHR (0.40) TSHRALDH1A1HPGD
SCHEMBL16788734 0.68 ZDHHC20 (0.46) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013051735-A1 UNDERLAY FILM COMPOSITION FOR IMPRINTS AND METHOD OF FORMING PATTERN AND PATTERN FORMATION METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2013-04-11 WO disclosed